Research Overview
Methanogenic Archaea
Methanogenic Archaea are ancient microorganisms that generate methane as a waste product of their normal cellular activities. This metabolism of environmental compounds by microorganisms involves generation of enzymes and enzymatic control mechanisms that can systematically break (and make) chemical bonds to extract energy and convert these materials into other carbon compounds and water.
The controlled expression of gene products involved in methanogenesis is essential for complete biomass conversion to generate...
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Research Description
Research Area: Anaerobic microbiology
Research Specialties: Regulation of gene expression in methane-producing Archaea, osmoregulatory mechanisms in marine and halophilic species of microorganisms, anaerobic bioremediation in the marine environment. Biology of Methanogenesis and Anaerobic Bioremediation:Regulatory pathways in the methanogenic Archaea with emphasis on catabolic gene expression; mechanisms of anaerobic reductive dechlorination in sediments impacted by PCBs and other organochlorianes; bioprocess scale-up of microorganisms from extreme environments.
Research interests
Regulatory pathways in the methanogenic Archaea
The Archaea, Bacteria and Eucarya represent the three primary phylogenetic lineages that diverged and evolved from a common progenote. The controlled...
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Representative Publications
Fagervold, S.K., H.D. May and K.R. Sowers. Microbial reductive dechlorination of Aroclor 1260 in Baltimore Harbor sediment microcosms is catalyzed by three phylotypes within the Chloroflexi. Appl. Environ. Microbiol. In press. [ABSTRACT]
Sowers, K.R. and K. Anderson. 2007. Molecular Genetics of Archaea. In: R. Cavicchioli (ed.), Archaea: Molecular Cell Biology. American Society for Microbiology, Washington, D. C., pp. 463-477. ISBN: 978-1-55581-391-8.
Sowers, K.R., S. DasSarma and P. Blum. 2007. Gene transfer in Archaea. In: C. A. Reddy, T. J. Beveridge, J. A. Breznak, G. A. Marzluf, and T. M. Schmidt (ed.), Methods for General and Molecular Microbiology. American Society for Microbiology, Washington, D. C. In press.
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