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Dr. Rosemary Jagus Research Overview Print Print   Email Email  

Translational Control
Genetic information is expressed when sequences of DNA are transcribed, ultimately generating, through a number of steps, messenger RNA which is then translated into proteins. Each gene defines one or more amino acid sequences that represent protein chains.

The process of translation is controlled throughout the process, including stages known as initiation, elongation, and release. These events involve complex interactions between complexes of proteins and nucleic acids, and since each of these molecules is itself a gene product, translation is ultimately under genetic control.

Zebrafish Development
Zebrafish is a model organism that is especially useful for studying cellular events in the early development of vertebrates. The ease of breeding and manipulation, and the characterization of the genome of zebrafish, make it an ideal system for the study of translational control in higher organisms.

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