Research OverviewNatural Products and Drug Discovery In medicine, biotechnology and pharmacology, drug discovery is the process by which drugs are discovered and/or designed. In the past most drugs have been discovered either by identifying the active ingredient from traditional remedies or by serendipitous discovery. A new approach has been to understand how disease and infection are controlled at the molecular and physiological level and to target specific entities based on this knowledge. The process of drug discovery involves the identification of candidates, synthesis, characterization... Complete Information... | Research DescriptionResearch Area: Marine Microbiology Research Specialties: Marine and estuarine microbiology, Marine bacteria and viruses,Climate, Vibrio cholerae, and related Vibrios. Research Interests Research in my laboratory focuses on molecular biology and microbiology of the aquatic environment: freshwater, estuarine, and marine microbial ecosystems. Our studies include marine biotechnology, i.e., increased productivity of the world oceans and alleviating human health problems by reducing cholera epidemics in developing countries through understanding of marine microbial ecosystems. Our research has also included studies of the effect of pollutants on the oceans, e. g., effects of waste dumping on marine and estuarine microbial ecosystems. This work includes effects of heavy metals, petroleum, domestic, and industrial wastes deposited in the New York Bight, Puerto Rico Trench, and the Gulf of Mexico... Complete Information... |
Representative PublicationsChakraborty, S., A. K. Mukhopadhyay, R. K. Bhadra, A. N. Ghosh, R. Mitra, T. Shimada, S. Yamasaki, S. M. Faruque, Y. Takeda, R. R. Colwell, and G. B. Nair. 2000. Virulence genes in environmental strains of Vibrio cholerae. Appl. Environ. Microbiol. 66:4022-4028 Colwell, R. 2000. The future of biocomplexity. Environmental Microbiology. 2:3-4. Colwell, R. 2000. The Role and Scope for an Integrated Community of Biologists. BioScience. 50:199-202. Complete Listing... |
