Research OverviewEconomically Important Viruses of Poultry and Fish The diagnosis, prevention and control of viral infections in poultry and fish are of global economic importance. Infectious Bursal Disease Virus (IBDV) is highly contagious among young chickens, and has high mortality. Infectious pancreatic necrosis virus (IPNV) is a pathogen of major importance in the fishing industry and aquaculture. The development of safe, economical and effective... Complete Information... | Research Description
Research Areas: Pathobiology, Biomolecular and Metabolic Engineering Research Specialties: Molecular biology and virology; cloning and expression of foreign genes; pathogenesis My laboratory is studying the molecular biology of economically important viruses of poultry and fish, and focuses on developing rational strategies for the diagnosis and control of viral infections. Infectious Bursal Disease Virus (IBDV) and infectious pancreatic necrosis virus (IPNV) are pathogens of major economic importance to the poultry and fish industry. IBDV causes severe immunodeficiency in young chickens, whereas IPNV causes pancreatic necrosis in fish. To develop a safe, economical, and effective subunit vaccine for both IBDV and IPNV, we have cloned and expressed the structural proteins, encoded by the large... Complete Information... |
Additional Info
Inventor of the Year Award and David B. Snyder Award * Secondary Appointment: Associate Professor, College of Veterinary Medicine, University of Maryland, College Park.
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Representative PublicationsSanti, N., Vakharia, V.N., Evenesen, O. 2004. Identification of putative motifs in the virulence of infectious pancreatic necrosis virus. Virology. 322(1):31-40. Abstract. Touris-Otero, F., Martinez-Costas, J., Vakharia,V.N., Benavente, J. 2004. Avian reovirus nonstructural protein microns forms viroplasm-like inclusions and recruits protein sigmaNS to these structures. Virology. 319(1):94-106. Abstract. Oshop, G.L., Elankumaran, S., Vakharia, V.N., Heckert, R.A. 2003. In ovo delivery of DNA to the avian embryo. Vaccine. 21:1275-81. Abstract. Complete Listing... |
