Research OverviewDisease Resistance in Plants Disease resistance in plants in part depends on the ability of the plant cells to recognize the invading pathogens. Since such recognition involves recognition of specific molecules, it is often under genetic control. Pseudomonas syringae Pseudomonas syringae is a bacterial pathogen that can affect a broad range of plant species, including several of economic importance... Complete Information... | Research DescriptionResearch Area: Pathobiology Research Specialties: Microbial pathogenesis; plant-microbe recognition; mechanisms of disease resistance; prokaryotic gene regulation and protein translocation Disease resistance in plants is attributable in part to a specific recognition process dependent upon resistance genes. Recognition of an invading pathogen results in the induction of cellular defense responses in the plant. These induced defense responses function to impede further invasion of the tissue by the pathogen. In plant pathogenic bacteria, such as Pseudomonas syringae, induction of defense response in resistant plants has been linked to the expression of hrp and avr genes. Efforts in my laboratory are focused... Complete Information... |
Representative PublicationsPirhonen, M. U., Lidell, M. C., Rowley, D. L., Lee, S. W., Jin, S., Liang, Y.,Silverstone, S., Keen, N. T., and Hutcheson, S. W. 1996. Phenotypic expression of Pseudomonas syringae avr genes in E. coli is linked to the activities of the hrp-encoded secretion system. Molecular Plant-Microbe Interactions. 9:252-260. Hutcheson, S. W., Heu, S., Jin, S., Lidell, M. C., Pirhonen, M. U., and Rowley, D. L. 1996. Function and regulation of Pseudomonas syringae hrp genes. In: Molecular Biology of Pseudomonads. (ed. T. Nakazawa et al.) ASM Press, Washington, D.C. pp. 512-521. Xiao, Y., Heu, S., Yi, J., Lu, Y., and Hutcheson, S. W. 1994. Identification of a putative alternate sigma factor and characterization of a multicomponent regulatory cascade controlling the expression of Pseudomonas syringae pv. syringae Pss61 hrp and hrmA genes. J. Bacteriol. 176:1025-1036. |