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DNA, RNA and protein molecules are not only capable of biological function but also are capable of self-organizing into the topologies which create the functions. This unique property of self-organization is the junction where chemistry crosses into biology. Scientists at CARB study basic questions at this critical junction: - How is DNA replicated?
- How do RNA and proteins self-organize into a functional topology?
- How do Proteins and RNA interact with other functional molecules to create the myriad and diverse chemistries needed for life?
The techniques needed to study these questions are specialized because all these processes occur on the nano-scale. CARB has assembled capability in important methodologies including fluorescence and absorption spectroscopy, rapid kinetic detection, analytical ultracentrifugation, surface plasmon resonance and microcalorimetry in order to detect interactions within and among molecules. Faculty: Dr. Edward Eisenstein Dr. Zvi Kelman Dr. Frederick P. Schwarz
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